Differential diagnosis. Obsessive compulsive disorder (OCD) – The obsessive thoughts and repetitive actions seen in OCD can appear This is especially true of albinism. Some people with hypopigmentation are at a higher risk for skin cancer. This is a broad category of differential diagnoses with variable symptomatology depending on the specific diagnosis. Pigmenting pityriasis alba. In these cases, the skin is more vulnerable to damage from ultraviolet rays. It is necessary to perform a clinical differential diagnosis of hypopigmented lesions, including vitiligo, idiopathic guttate hypomelanosis, tinea versicolor, and postinflammatory hypopigmentation. a. Case presentation A 7-year-old girl presents with a small number of hypopigmented macules on her back that have been present for about three months (Figure 1). The macules are well circumscribed and each has a central raised lesion. 1 Frequency of the condition is much lower in … The pigment cells or melanocytes are located at the base of the epidermis and produce the protein melanin.Melanin is carried by keratinocytes to the skin surface. DISCUSSION. When faced with a patient with hypopigmented macules, the differential diagnosis should include tinea versicolor, pityriasis alba, vitiligo, tuberculoid leprosy, and idiopathic guttate hypomelanosis. ... hypopigmented macules in this 6-year-old child with pityriasis alba. The hypopigmented macules progress to full depigmentation. Erythema, scale, and papules within these macules and patches are variable. BS consists of asymptomatic, small, irregular, hypopigmented macules characterized by a normal histological appearance, which are usually found in individuals aged 20-40 and more frequently in women than men. Differential diagnosis Conditions to include in the differential diagnosis include the following. 1,2 The skin surrounding the lesions may be normal or mildly erythrocyanotic. Hypopigmented MF presents with hypopigmented macules and patches. The differential diagnosis is challenging as TFI resemble many other dermatologic conditions. Nevus depigmentosus. Lesions often occur on the head, neck, upper extremities, trunk, and buttocks. Idiopathic guttate hypomelanosis is a common but underreported condition in elderly patients that usually presents with small, discrete, asymptomatic, hypopigmented macules. The frequency of IGH increases with age. Pigmentation of the skin normally varies according to racial origin (see Fitzpatrick phototypes) and the amount of sun exposure.Pigmentation disorders are often more troublesome in skin of colour.. Lesions of pityriasis alba are usually bilateral and located on the face, arms, and neck. For example, macules can be moles (which are hyperpigmented, or darker, relative to the skin) or vitiligo lesions (which are hypopigmented or depigmented, or lighter, relative to the skin). The differential diagnosis of pityriasis alba includes the following: Postinflammatory pigment alteration. Quadrichrome vitiligo features a fourth, dark-brown pigment, which surrounds hair follicles. Introduction. A well-defined, hypopigmented, irregularly shaped, confluent macules forming a patch that is usually found on the trunk; It presents at birth or early in childhood and persists in to adulthood remaining unchanged; Stroking, rubbing, or warming induces erythema of the adjacent normal skin Hypochromic naevus (naevus depigmentosus). Extremities, trunk, and buttocks has a central raised lesion hypopigmented macules differential diagnosis appear Introduction presents with small, discrete asymptomatic... 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