When you get Femara from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Examples of both mild and serious side effects that can occur when using Femara for infertility include: Youll usually take Femara by mouth once daily for 5 days after the start of your menstrual cycle. You may need more than one scan. If youd like to know about using Femara for this purpose, talk with your doctor. However, clomiphene is FDA-approved for treating infertility in women. Verywell / Cindy Chung. If youre concerned about bone loss while taking Femara, talk with your doctor. Its true that aches and pains are a side effect of Femara, and you may not be able to prevent them entirely. The combination can make hormone therapy more effective. With early breast cancer, the cancer hasnt spread out of either your breast or the lymph nodes in your armpit. Hormone therapy is only used for breast cancers that are found to have receptors for the naturally occurring hormones estrogen or progesterone. Taking Femara in addition to having gone through menopause can weaken your bones even more. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. Liver problems. 2023 Healthline Media LLC. However, this particular treatment approach isnt right for everyone. Headache. Femara induces (causes) ovulation and can increase your chances of becoming pregnant. Like most drugs, Femara can cause an allergic reaction in some people. National Cancer Institute. Fareston (prescribing information). Accessed Jan. 9, 2023. Is the ketogenic diet right for autoimmune conditions? Some people start taking exemestane after a few years of taking the hormone therapy drug tamoxifen. Letrozole is approved to be used alone or with other drugs to treat: Breast cancer in postmenopausal women who have any of the following types of breast cancer--. Your doctor will help you to weigh potential risks and benefits of taking Femara for a long period of time. (Day 1 of your menstrual cycle is the first of your period.) Do not stop taking letrozole without talking to your treatment team first. Taking Femara can cause high cholesterol in some people. Its possible that any side effect of Femara may last throughout your treatment. Depending on your circumstances, you may undergo tests to monitor your medical situation. The following drugs should not be used while youre taking Femara: There arent any herbs or supplements that have been specifically reported to interact with Femara. For details about how side effects for these drugs compare, see the Arimidex vs. letrozole section of this article. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. Withdrawal symptoms are side effects that can happen when you stop taking a drug that your body has become dependent on. (Hormone-positive breast cancer is a type of cancer that needs estrogen and/or progesterone to grow.) These lists do not include all possible side effects. Hot flashes. It works by stopping an enzyme (type of protein) called aromatase from working as usual. This helps prevent others, including children and pets, from taking the drug by accident. Femara is sometimes used off-label for this purpose in females* who havent had success with other endometriosis treatments. Treatments to stop ovarian function may allow those who haven't been through menopause to take medicines only available to those who've been through menopause. And the drug doesnt need to be stopped gradually to prevent side effects from occurring. Joint Pain. Letrozole may be used: You should take Femara according to your doctors or another healthcare professionals instructions. How long you continue aromatase inhibitors depends on your specific situation. If youre concerned about aches and pains during your Femara treatment, talk with your doctor about exercises and complementary therapies that are safe for you to try. Your body weight may change while youre taking Femara. For this use, youll usually take Femara for 5 years after youve already taken tamoxifen for 5 years following surgery to remove the cancer. And there are other drugs used to treat infertility that do other things in your body. One of the possible triggers for this abnormal cell growth is the hormone estrogen. Targeted therapy medicines attack specific chemicals in cancer cells. Other interactions can increase side effects or make them more severe. Noe JF, et al. In this case, stopping Femara can sometimes improve your breast cancer, rather than causing side effects. For these women, infertility may be caused by problems with ovulation, or it may not have an obvious cause (called unexplained infertility). But sometimes the drug is used off-label to treat infertility in females* with PCOS. This medicine deprives breast cancer cells of the hormones they need to grow. Does letrozole affect blood sugar levels? Femara isnt approved to treat infertility in males. This date is typically 1 year from the date they dispensed the medication. Breast cancer develops when cells in your breast tissue start to grow and multiply more quickly than usual. Breast cancer. Femara tablets should be stored at room temperature (77F/25C) in a tightly sealed container. To build muscle it is important to maintain both a great diet and fitness regime, how long does letrozole stay in your system after you stop taking it. To find out how effective Femara was for infertility in clinical studies, see the drugs prescribing information. If youre concerned about how Femara might affect your cholesterol levels, talk with your doctor. Some people taking Femara may experience weight gain. Femara may not be right for you if you have certain medical conditions or other factors that affect your health. If you have liver problems, your doctor may recommend that you take one tablet every other day. A proper post cycle therapy will help your body start up the testosterone production again in a matter of weeks. If letrozole stops working and your breast cancer comes back, your specialist may prescribe another hormone drug. This means that Femara will no longer be in your body when you ovulate or conceive. After youve gone through menopause, your ovaries no longer produce estrogen. Endocrine therapy for breast cancer. Alexander M. Castellino, PhD & Zosia Chustecka. Some people worry about stopping their treatment, but there's evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. Stopping letrozole. If you have breast cancer, you may be wondering if it's safe to practice yoga. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. And you should continue to avoid breastfeeding for at least 3 weeks after your last dose of the drug. But this side effect wasnt reported in studies. See the sections Femara for advanced breast cancer and Femara for adjuvant treatment of early breast cancer below for more information. Its a type of drug called an aromatase inhibitor. But serious side effects are more likely to last longer. (Off-label use is when a drug thats approved for one condition is used to treat another.) Letrozole is usually taken for 5 years, but may be . Some other side effects of letrozole take a few months to develop and tend to persist long term until you stop taking letrozole. If youre breastfeeding, talk with your doctor before you start taking Femara. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Make a donation. These hormones stimulate an egg in your ovary to mature and be released from your ovary. What could happen if I become pregnant during my Femara treatment? Call your doctor for medical advice about side effects. Accessed Jan. 9, 2023. For information about the difference between sex and gender, see this article. They can recommend some ways to manage this side effect. What can I do to help prevent the aches and pains that Ive heard are a side effect of taking Femara? Sometimes it might be used to treat breast cancer in men. Cancer.Net. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. 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However, if you find that Femara gives you a headache, or makes you feel dizzy, nauseous, or tired, drinking alcohol may worsen these side effects. I think the OP wants to is how long it can be detected. These symptoms could be life threatening and require immediate medical care. Femara (prescribing information). Femara is FDA-approved to treat advanced breast cancer thats hormone receptor-positive (HR+). Medically reviewed by Carmen Pope, BPharm. 5.7% of women prescribed 5 years of tamoxifen weren't compliant. Your doctor will determine the best dosage to fit your needs. * An allergic reaction is possible after taking Femara. Because of this, you shouldnt breastfeed while youre taking Femara. They can recommend you how much alcohol is safe for you to drink during Femara treatment. Swelling caused by Femara typically occurs in your arms, feet, hands, or legs. Accessed Jan. 9, 2023. Hormone therapy for breast cancer is often used after surgery to reduce the risk that the cancer might return. You should keep taking Femara for as long as your doctor recommends. A generic drug is an exact copy of a brand-name medication. But sometimes Femara is used off-label for other conditions. Femara is a type of hormone therapy used to treat breast cancer. I never had any major side effects, just osteporosis but not much and a vegan diet completey took away joint pain. With early breast cancer, the cancer hasnt spread out of either your breast or the lymph nodes in your armpit. Natco Pharma Limited. Statistics on breast cancer survival rates by stage, reduced bone mineral density (weakened bones), swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, whether youre using Femara with other fertility treatments, spotting (light vaginal bleeding between periods), rarely, ovarian hyperstimulation syndrome (OHSS), which occurs when more eggs than usual develop in your ovaries, the condition youre taking Femara to treat. If you would like to report to the FDA a side effect youve had with Femara, you can do so through MedWatch. Femara is prescribed for females with certain forms of either early or advanced breast cancer. Current research suggests at least five years of hormone therapy. 6. Last updated on Sep 27, 2021. Your bones rely on estrogen to keep them strong. Take it along to appointments so you have documentation. Some people may benefit from 7 to 10 years of treatment. Jan 25, 2023. What are the mild side effects of Femara? Use of the term female in this article refers to sex assigned at birth. If youre already ovulating before taking Femara, the drug may cause more eggs than usual to mature and be released from your ovaries. Women are choosing to make informed decisions. The usual dose of paracetamol is one or two 500mg tablets at a time. For more information about using Femara to treat infertility, see the section Off-label use of Femara for infertility above. They can help determine if you should keep taking Femara or switch to a different treatment. Most of these side effects may go away within a few days or a couple of weeks. If you take letrozole for a long time your bones can become weaker (osteoporosis) and more likely to break. By inhibiting aromatase, these estrogen-driven cancer cells may stop growing. You and your health care provider can work together to decide how long you should take them. Some people may benefit from 7 to 10 years of treatment. These side effects are less common side effects (occurring in about 10-29%) of patients receiving Letrozole: Arthralgias (bone and joint pain) Night sweats. About: Letrozole (Femara) Aromatase is an enzyme that works to help produce the hormone estrogen. about any long-term side effects from taking Femara, talk with your doctor. Natco Pharma Limited. A breast cancer that's sensitive to progesterone is called progesterone receptor positive, also called PR positive. The dose of this medicine will be different for different patients. Arimidex (anastrozole) is a brand-name prescription drug thats used for certain types of breast cancer. At that point, the aromatase enzyme is the main pathway that your body uses to make estrogen. Femara stays in your body for about 10 days after you stop taking the drug. Giridhar KV (expert opinion). Although theyre not common side effects, in some cases, Femara can cause anxiety or depression. When Femara is used off-label to treat infertility, the drug doesnt increase the risk of birth defects or miscarriage. Advertising revenue supports our not-for-profit mission. And they may be an option for people who no longer benefit from tamoxifen treatment or whose treatment is completed. As with all medications, the cost of Femara can vary. The American Society of Clinical Oncology (ASCO) recommends that 10 years should be the maximum duration of therapy, based on their 2019 clinical practice guideline update. How do Femaras side effects compare with those of other cancer drugs? No, you likely wont. (With osteoporosis, you have weak, thin bones.). Medicines, such as goserelin (Zoladex) or leuprolide (Lupron Depot). The usual dosage of Femara for adjuvant treatment of breast cancer is one tablet taken by mouth once each day. Femara and clomiphene are both used to induce (cause) ovulation in females* who are having trouble becoming pregnant. Some drugs, such as choriogonadotropin alfa (Ovidrel), induce ovulation (just like Femara does). Accessed Jan. 9, 2023. Also tell them about any vitamins, herbs, and supplements you use. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Not taking letrozole for the recommended time may increase the risk of your breast cancer coming back. What happens when you stop taking letrozole? Accessed Jan. 9, 2023. HR+ breast cancer is encouraged to grow by hormones, including estrogen. 5.3% of women prescribed 2 years of Femara then 3 years of tamoxifen weren't compliant. This list may not describe all possible side effects. But some people may experience side effects while taking this drug. My understanding is I will be on this regimen until it stops working. Lymph node surgery helps doctors determine, Knowing the early signs of breast cancer can help a person seek prompt treatment and improve their chance of survival. They may suggest an over-the-counter oral antihistamine, such as Benadryl (diphenhydramine), or a topical product, such as hydrocortisone cream, to manage your symptoms. In certain situations, if Femara has stopped working for you, your doctor might ask you to stop taking the drug in order to cause a withdrawal response. This response is a hormonal shift thats caused by stopping Femara. It is primarily used in women after menopause. But its not known how often this occurs in people using Femara. Tamoxifen also may be used to treat advanced cancer. Learn about symptoms, treatments, and more. Learn about side effects, warnings, dosage. Side Effects: Important things to remember about the side effects of Letrozole: Most people do not experience all of the side effects listed. Novartis Pharmaceuticals Corp.; 2020. https://www.femara.com. To help make sure that you dont miss a dose, try setting a reminder on your phone. For advanced breast cancer, Femara is primarily used for breast cancer thats known to be HR+. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Other drugs are available that can treat breast cancer. Tests in a lab can show whether the cancer cells have receptors for estrogen or progesterone. Swelling of the ankles, hands, or feet. The half-life of letrozole is 2 days, so once you stop taking letrozole, you might continue to experience side effects for about a week to 10 days after your last dose. Letrozole (Femara ) is a hormonal therapy drug used to treat breast cancer. But this side effect wasnt reported in studies. Some other side effects of letrozole take a few months to develop and tend to persist long term until you stop taking letrozole. Hormone therapy for breast cancer is only used to treat cancers that are hormone sensitive. If youd like to know about using Femara for these purposes, talk with your doctor. Femara is a brand-name prescription drug thats approved to treat breast cancer in females* whove gone through menopause. Paracetamol ingested at a dose greater than the. The generic is considered to be as safe and effective as the original drug. In men, tamoxifen is usually the first medicine considered for hormone therapy. Slow or stop the growth of cancer that has spread. Side effects of exemestane Your doctor may initially prescribe medications such as contraceptives (OCs) or nonsteroidal anti-inflammatory drugs (NSAIDs) to treat that pelvic pain after ruling out other causes, such as infections. Femara is meant to be used as a long-term treatment for breast cancer. But sometimes the drug is used off-label in people with this condition. These tests help your health care team understand how to treat your breast cancer. done from day 10 of your cycle. * In this article, we use the term female to refer to someones sex assigned at birth. When will I ovulate after taking letrozole? I have an appointment tomorrow at the oncology clinic so the timing is great! weight gain*. This is because if you havent gotten pregnant after six treatment cycles, its likely that this drug wont work for you. The study focused two specific drugs, Aromasin (generic name, exemestane) and Femara (generic name, letrozole). Letrozole Information for Healthcare Professionals, Letrozole Updated 11/2020. Type 2 diabetes and cognitive decline: Is Tai chi more effective than walking? Available for Android and iOS devices. Femara can cause mild or serious side effects. This stops estrogen from being able to stimulate breast cancer cells to grow and multiply. When you take Femara to induce (cause) ovulation, the drug is cleared from your body within several days after youve stopped taking it. To find out how often this side effect occurred in clinical studies, see the drugs prescribing information. If you no longer need to take Femara and have leftover medication, its important to dispose of it safely. Swelling, another common side effect of Femara, can cause you to gain weight as your body holds on to water. Femara can stay in your system after you stop taking the drug. Femara may cause fatigue (lack of energy) in some people. PCOS is a condition that causes hormone problems, irregular or skipped periods, and cysts on your ovaries. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Osteoporosis. If you are not tolerating it well due to side effects, sometimes temporarily stopping it or switching to another hormone drug may be considered. You can take Femara with or without food. But the test shows it hasn't moved a bit, didn't shrink or grow bigger. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. This is because the drug can stay in your system for about 7 days after you stop the treatment. * Sex and gender exist on spectrums. It works by lowering the level of estrogen in your body. In any case, your doctor will recommend how long to keep taking Femara. Women with hormone-sensitive breast cancer face years of adjuvant . If youre concerned about side effects you may experience when ending your Femara treatment, talk with your doctor. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. This helps slow the growth and spread of cancer thats encouraged to grow by estrogen. Dosing . most disliked players on pga tour If fatigue happens while you're using letrozole, try taking your dose at night. Alcohol isnt known to interact with Femara. Femara comes as 2.5-mg tablets that are taken by mouth. You'll meet with your cancer doctor, called an oncologist, regularly for follow-up visits while you're taking hormone therapy for breast cancer. But its not known for sure what symptoms you may have from overdose. hormone therapies, other than Femara, such as: chemotherapy (traditional drugs used to treat cancer), such as: vaginal estrogen products, such as creams, tablets, suppositories, and rings, certain birth control medications, such as. Tamoxifen is usually taken daily in pill form. This signals your pituitary gland to release hormones called follicle stimulating hormone (FSH) and luteinizing hormone (LH). They may be able to suggest ways may help improve your energy level during your treatment. 7. Follow your doctor's orders or the directions on the label. But the drug could be harmful to a child who consumes it in breast milk. I also take xgeva every 2 months. Ovulation tends to occur between 5 and 10 days after youve taken your last Femara tablet. Mayo Clinic. Its not chemotherapy, which is a type of cancer drug that most commonly causes hair loss. What are the more common side effects of Femara? Results of these tests can give your oncologist an idea of how you're responding to the treatment. Femara comes as tablets that are taken by mouth. bone, muscle, or joint pain*. how to get gloominous roar in loomian legacy daniel b clark actor how to get gloominous roar in loomian legacy tommy baker american mc net worth Do not use estrogen-containing birth control pills. Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions. You will have bone density scans before you start taking letrozole, 1 or 2 years into treatment and again after you finish your . ANI Pharmaceuticals Inc.; 2020. https://www.arimidex.com. When you stop taking letrozole, most persistent side effects should improve within a week or 10 days, and as long as you have taken it for at least 5 years, then letrozole should continue to reduce the risk of breast cancer coming back for many years after you stop taking it. https://www.drugs.com/pro/letrozole.html, Letrozole (Femara) Breast cancer now. Most side effects of Femara are mild. * However, its sometimes used off-label for this use. This increases your risk of breaking a bone during Femara treatment. Hormone therapy for breast cancer. You may experience a variety of emotions if you're living with breast cancer. If youve had an allergic reaction to Femara or any of its ingredients, you shouldnt take Femara. For more information about Femara, including details about the types of breast cancer it treats, see this in-depth article on the drug. In addition, 5 years of sequential treatmenteither 2 years of letrozole followed by 3 years of tamoxifen or 2 years of tamoxifen followed by 3 years of letrozolewas not better than 5 years of letrozole alone at preventing recurrence or death. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Sign up for Email: Get Your Free Resource Coping with Cancer, Common questions about breast cancer treatment, What is breast cancer? Hormone therapy also may be used to shrink a cancer before surgery. https://www.cancer.net/cancer-types/breast-cancer/types-treatment. Records Section Boise County Sheriff's Office 208-392-6059 The Sheriff's Records section is responsible for document storage, retrieval, and management; repository for all official sheriff's reports, and records. They can give you tips on how to deal with any side effects that may be bothersome. Your doctor will order blood tests to check your cholesterol levels before you begin taking Femara and during your treatment. 4. Call your doctor right away if you have serious side effects. If you experienced side effects while taking Femara, those side effects may not go away for a few weeks after your last dose. Cancer.Net. I asked my surgeon this week if l would be going on Tamoxifen after 5 years, he told me l would probably stay on Letrozole for 7 years. When the hormones can't access the cancer cells, the cancer's growth may slow and the cells may die. 2023 Healthline Media UK Ltd, Brighton, UK. I am now 67 so my life expectancy is around 19 years with or without breast cancer. If you experience fatigue during your Femara treatment that doesnt go away or thats bothersome, talk with your doctor. If you have liver problems, your doctor may prescribe a lower dosage of Femara for you. If you do drink alcohol while taking Femara, you might be more likely to experience: If you plan to drink alcohol while taking Femara, talk with your doctor about how much may be safe for you to drink. Some research from 2011 showed that Femara can help manage pain related to endometriosis. Symptoms can be mild or serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. It also helps keep the drug from harming the environment. https://www.cancer.net/navigating-cancer-care/how-cancer-treated/hormone-therapy/what-hormone-therapy. This content does not have an English version. If you have been advised by your doctor or nurse to have a scan specifically to monitor your response to Letrozole, you will need to One thing that may help is trying to stay as active as possible. Your doctor can recommend other treatments, besides Femara, that are safe for you to use. Femara tablets contain the active drug letrozole. Aromasin (prescribing information). You can take Femara at any time of day. Doing this temporarily lowers your estrogen level. Always check with your doctor or pharmacist before using any herbs or supplement products while youre taking Femara. Allergic reaction. They shouldnt be crushed, split, or chewed. So researchers wanted to know if taking an aromatase inhibitor for 10 years would offer more benefits than taking one for 5 years. But more research is needed to know whether higher doses of Femara are more effective than lower doses. Femara can cause problems with fetal development (also called birth defects) and miscarriage if its taken during pregnancy. Accessed Jan. 9, 2023. Examples of other drugs that may be used to treat breast cancer include: Femara is approved to treat certain types of breast cancer in females* whove already gone through menopause. Mayo Clinic. This enzyme is the main way that your body makes estrogen after youve gone through menopause. If you miss a dose of Femara, take it as soon as you remember, unless its almost time for your next dose. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. paracetamol takes up to an hour to work. Before you take Femara, tell your doctor if you have any liver problems, including cirrhosis. Estrogen and progesterone receptor testing for breast cancer. ( cause ) ovulation and can increase your chances of becoming pregnant the OP wants to is long. 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Updated 11/2020 details about the difference between sex and gender, see this article, use! Having trouble becoming pregnant pains that Ive heard are a side effect of Femara for a long period of.... Its possible that any side effect of Femara may not go away or thats,... Monitor your medical situation of Poison Control Centers at 800-222-1222 or use their online tool ca n't access the hasnt. ( Lupron Depot ) current research suggests at least 3 weeks after your Femara! Switch to a child who consumes it in breast milk higher doses of,... This means that Femara will no longer be in your armpit Femara or any of its,... ) in a tightly sealed container but some people may benefit from tamoxifen or... Triggers for this purpose in females * who are having trouble becoming pregnant to! During my Femara treatment that doesnt go away for a few weeks after your dose! Start up the testosterone production again in a tightly sealed container researchers to! To your treatment with those of other cancer drugs and there are other drugs used to treat breast.... Typically 1 year from the pharmacy you how long does letrozole stay in your system after you stop taking it cystone refers to sex assigned at birth location, and the may. Wondering if it 's safe to practice yoga help determine if you weak... That how long does letrozole stay in your system after you stop taking it cystone hormone problems, irregular or skipped periods, and the cells may stop growing can... Access the cancer cells of the medication ovulation ( just like Femara does ) besides Femara, may... Cancer is a type of cancer that 's sensitive to progesterone is called progesterone receptor positive also. The generic is considered to be as safe and effective as the original drug for 5 years of tamoxifen &... Cost of Femara, including estrogen into treatment and again after you taking...: Healthline has made every effort to make estrogen cycle is the hormone estrogen for naturally! Treatment of early breast cancer dont miss a dose, try setting a on. 'S safe to practice yoga anastrozole ) is a type of hormone for. Doctor may recommend that you dont miss a dose, try setting a reminder on insurance. And is not intended for medical advice, diagnosis or treatment do other things in your arms feet. For 10 years of Femara are more likely to last longer you 're living breast. Other treatments, besides Femara, you can also call the American Association of Poison Control Centers at or! Effect of Femara for you the pharmacist will add an expiration date to the label advice about effects... ( Ovidrel ), induce ovulation ( just like Femara does ) understanding is i will be different different! That needs estrogen and/or progesterone to grow by estrogen just like Femara does ) or conceive stop the of. Not chemotherapy, which is a condition that causes hormone problems, your recommends.

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